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Our tests can give you insight aboutBone Health

Osteoporosis: risk assessment, prevention and effective treatment

  • Genetic assessment of your osteoporosis risk
  • Analysis of more than 3 relevant genetic variations
  • Assessment of calcium absorption capacity to absorb calcium from food
  • Adapted nutrition and prevention program for osteoporosis
  • Effectiveness assessment of various therapies (bisphosphonate, raloxifene, alendronate, hormones)
  • Analysis of more than 12 genetic variations predicting the effectiveness of more than 18 relevant drugs
  • Increased treatment success through customized therapy

Osteoporosis is a disease that affects the bones. It causes bones to lose mass and strength, and makes them more fragile and easier to fracture. Even in normal development, bones become more likely fracture with age. Bones reach maximum strength at about the age of 30, and bone mass decreases moderately after that time. However, some genetic traits lead to reduced bone strength, which increases the risk of osteoporosis and bone fractures, especially of the hips, forearms and vertebra. This risk grows with age.

Most fractures involve the hips, forearms and vertebrae. In normal development these bones grow throughout childhood and reach maximum strength at about age 30. After that time, bone mass gradually decreases, leading to somewhat more brittle bones. However, some traits in the genes that are responsible for bone formation can cause your bones to become unusually fragile over time. As you age, this leads to increased bone loss and fractures. About 80% of osteoporosis cases occur in post-menopausal women, mainly because the body no longer produces the bone-protective hormone estrogen. The disease is very common: one in three women over the age of 50 is diagnosed with osteoporosis. As estrogen, the female sex hormone, plays a significant role for women in the formation of bone, women who have had lower estrogen levels throughout their life (e.g. due to a late start of menstruation or premature menopause) are particularly at risk.

The osteoporosis is a common disease for men over the age of 70. Although women are more often affected by osteoporosis, this disease affects both sexes, and its development is accelerated by certain risk factors such as poor diet and unhealthy lifestyle. Not only calcium, but also numerous other micronutrients (such as minerals, amino acids, and vitamins) are important in maintaining healthy bones. Bones have the capability to store calcium, but these reserves are depleted in the case of nutritional deficiencies, for providing the calcium needed for other important processes in the body. Vitamin D also plays an important role in the absorption of calcium from food.