- Analysis of the three relevant genetic variations
- Determination of genetic risk for high blood pressure
- Personalized prevention program for lowering blood pressure
- Analysis of over 6 genetic variations predicting the effectiveness of 12+ relevant drugs
- Better treatment through optimal drug therapy
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Hypertension is a condition in which the blood pressure of the vascular system is chronically elevated. A chronic systolic blood pressure higher than 140 mmHg or a diastolic blood pressure greater than 90 mmHg (both measured after 10 minutes of sitting) are considered high blood pressure. This method of measurement is the current standard, because the blood pressure is often decreased after sitting down, and increased where physical activities are performed.
Hypertension is a major risk factor in the development of atherosclerosis, or hardening of the arteries, especially if other risk factors such as severe obesity, diabetes, or elevated cholesterol or triglyceride levels occur. The resulting cardiovascular diseases, such as coronary heart disease (CHD), heart attack, heart failure, kidney failure, stroke, and vascular disease cause about 45% of deaths in men and 50% of deaths in women.
Several genetic variations have been identified that can significantly increase the risk of hypertension. Through an analysis of these polymorphisms, the risk of developing hypertension can be determined, and reduced with specific preventive measures. The genetic analyses also helps in identifying the most effective therapy for lowering blood pressure.